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Retinyl Palmitate

Retinyl Palmitate is a active, antioxidant, skin conditioning used in cosmetic and personal-care formulation. Typical use level is 0.01%–1%. It is oil-soluble. Stable in the pH 4–7 range.

At a glance

CAS number
79-81-2
INCI name
Retinyl Palmitate
Function
active, antioxidant, skin conditioning
Typical use level
0.01%–1%
Solubility
oil
Stable pH
4–7

CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.

Also known as

Vitamin A Palmitate Retinol Palmitate Vitamin A Ester All-trans-retinyl palmitate

Compatibility

Works well with:
Tocopheryl Acetate Tocopherol Niacinamide Hyaluronic Acid Squalane Dimethicone

Use caution with:
Benzoyl Peroxide Alpha Hydroxy Acids Ascorbic Acid

Retinyl palmitate is sensitive to oxidation and UV degradation; antioxidants such as tocopherol stabilize it and should be included in formulations. It can be destabilized by strong oxidizing agents like benzoyl peroxide and may be less effective when combined with high concentrations of AHAs due to pH mismatch. Packaging in opaque, airless containers is strongly recommended to preserve potency.

Formulation notes

Retinyl palmitate is an ester of retinol (vitamin A) and palmitic acid, serving as a milder, more stable precursor to retinol in cosmetic formulations. It is converted in the skin to retinol and subsequently to retinoic acid, supporting cell turnover, collagen synthesis, and anti-aging benefits, though with lower potency and irritation risk compared to retinol or retinoic acid. Formulators should note photosensitivity concerns — some studies suggest potential pro-oxidant activity under UV exposure, so daytime use products should include appropriate UV filters and antioxidants.

Frequently asked questions

What is Retinyl Palmitate?

Retinyl Palmitate is a active, antioxidant, skin conditioning used in cosmetic and personal-care formulation. Typical use level is 0.01%–1%. It is oil-soluble. Stable in the pH 4–7 range.

What is Retinyl Palmitate used for?

Retinyl Palmitate is used as active, antioxidant, skin conditioning in cosmetic and personal-care formulations.

What is the typical use level of Retinyl Palmitate?

Retinyl Palmitate is typically used at 0.01%–1% in the finished formulation. Always confirm against your supplier's technical data sheet.

What is the CAS number of Retinyl Palmitate?

The CAS registry number for Retinyl Palmitate is 79-81-2. Its INCI name is Retinyl Palmitate.

At what pH is Retinyl Palmitate stable?

Retinyl Palmitate is generally stable in the pH 4–7 range.

What ingredients are compatible with Retinyl Palmitate?

Retinyl Palmitate works well with Tocopheryl Acetate, Tocopherol, Niacinamide, Hyaluronic Acid, Squalane, Dimethicone. Use caution when combining it with Benzoyl Peroxide, Alpha Hydroxy Acids, Ascorbic Acid.

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