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Ascorbyl Glucoside

Ascorbyl Glucoside is a active, antioxidant, skin brightening used in cosmetic and personal-care formulation. Typical use level is 0.5%–3%. It is water-soluble. Stable in the pH 4–7 range.

At a glance

CAS number
129499-78-1
INCI name
Ascorbyl Glucoside
Function
active, antioxidant, skin brightening
Typical use level
0.5%–3%
Solubility
water
Stable pH
4–7

CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.

Also known as

AA2G Vitamin C Glucoside 2-O-alpha-D-Glucopyranosyl-L-ascorbic acid Ascorbic Acid 2-Glucoside

Compatibility

Works well with:
Niacinamide Hyaluronic Acid Kojic Acid Alpha Arbutin Glycerin Tocopherol

Use caution with:
High-concentration direct acids at low pH

Ascorbyl Glucoside is notably more stable than L-ascorbic acid and is compatible with a broad range of actives including niacinamide, which can cause issues with unstabilized ascorbic acid forms. It should be added to the water phase and kept within pH 4–7 to prevent hydrolytic degradation. Avoid prolonged exposure to very low pH environments, which can cleave the glycosidic bond and accelerate breakdown.

Formulation notes

Ascorbyl Glucoside is a stable, water-soluble vitamin C derivative in which glucose is bonded to ascorbic acid via a glycosidic linkage. Upon skin absorption, cutaneous glucosidases cleave the bond to release free L-ascorbic acid, delivering antioxidant protection, melanogenesis inhibition, and collagen synthesis stimulation. Formulators favor it over L-ascorbic acid for its significantly improved stability, broader pH tolerance, and gentler skin profile.

Frequently asked questions

What is Ascorbyl Glucoside?

Ascorbyl Glucoside is a active, antioxidant, skin brightening used in cosmetic and personal-care formulation. Typical use level is 0.5%–3%. It is water-soluble. Stable in the pH 4–7 range.

What is Ascorbyl Glucoside used for?

Ascorbyl Glucoside is used as active, antioxidant, skin brightening in cosmetic and personal-care formulations.

What is the typical use level of Ascorbyl Glucoside?

Ascorbyl Glucoside is typically used at 0.5%–3% in the finished formulation. Always confirm against your supplier's technical data sheet.

What is the CAS number of Ascorbyl Glucoside?

The CAS registry number for Ascorbyl Glucoside is 129499-78-1. Its INCI name is Ascorbyl Glucoside.

At what pH is Ascorbyl Glucoside stable?

Ascorbyl Glucoside is generally stable in the pH 4–7 range.

What ingredients are compatible with Ascorbyl Glucoside?

Ascorbyl Glucoside works well with Niacinamide, Hyaluronic Acid, Kojic Acid, Alpha Arbutin, Glycerin, Tocopherol. Use caution when combining it with High-concentration direct acids at low pH.

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