At a glance
- CAS number
- 1406-66-2
- INCI name
- Tocopherol
- Function
- antioxidant, emollient, active
- Typical use level
- 0.01%–1%
- Solubility
- oil
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
Tocopherols Methyltocols Lasar UnoVit VitaE Vitamin Emp E Vicotrat Micorvit E E Mulsin VitaPlus E Vitamin E mp Vitamin E-mp
Compatibility
Works well with:
Vitamin C (stabilized derivatives) Retinol Niacinamide Squalane Jojoba Oil Rosehip Oil BHT Ferulic Acid Coenzyme Q10 Lecithin
Use caution with:
L-Ascorbic Acid High-concentration Iron Salts Strong Oxidizing Agents
L-Ascorbic Acid in its pure form can act as a pro-oxidant in combination with Tocopherol under certain conditions, though stabilized vitamin C derivatives are generally compatible. High concentrations of iron salts or strong oxidizing agents can degrade Tocopherol and reduce its antioxidant efficacy. Tocopherol works synergistically with Ferulic Acid and stabilized Vitamin C, which can regenerate spent Tocopherol.
Formulation notes
Exists as alpha, beta, gamma, and delta isomers; alpha-tocopherol is most biologically active. Use at low levels (typically 0.05–0.5%) in leave-on products to protect formula lipids from oxidative rancidity. EU Cosmetics Regulation permits up to 0.5% in rinse-off products due to potential sensitization concerns at higher levels. Best added to the oil phase; protect from light and heat during processing.
Related ingredients
- Tocopheryl AcetateAntioxidant
- BakuchiolActive
- BisabololActive
- Ascorbic AcidAntioxidant
- AstaxanthinAntioxidant
- Azelaic AcidActive