At a glance
- CAS number
- 111-01-3
- INCI name
- Squalane
- Function
- emollient, solvent, active
- Typical use level
- 1%–100%
- Solubility
- oil
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
2,6,10,15,19,23-Hexamethyltetracosane Perhydrosqualene Cosbiol Robane Dodecahydrosqualene Hexamethyltetracosane Spinacane Vitabiosol Tetracosane, 2,6,10,15,19,23-hexamethyl- Hexamethyl tetracosane Pripure 3759 footcream
Compatibility
Works well with:
Niacinamide Retinol Vitamin C Hyaluronic Acid Ceramides Peptides AHA/BHA Benzoyl Peroxide Jojoba Oil Argan Oil
Squalane is exceptionally chemically inert and broadly compatible with nearly all cosmetic ingredients across oil and water phases. It is non-comedogenic, oxidatively stable, and does not saponify, making it safe alongside actives and preservatives. No significant incompatibilities are widely documented under typical cosmetic formulation conditions.
Formulation notes
Plant-derived (typically from sugarcane or olive) squalane is a fully saturated hydrocarbon; unlike squalene (CAS 111-02-4), it is highly resistant to oxidation. No regulatory use restrictions apply in cosmetics. Suitable for all skin types including sensitive and acne-prone skin. Can be used as a standalone facial oil (100%) or incorporated into emulsions, serums, and lip products.
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