At a glance
- CAS number
- 52225-20-4
- INCI name
- Tocopheryl Acetate
- Function
- antioxidant, active, emollient
- Typical use level
- 0.1%–1%
- Solubility
- oil
- Stable pH
- 4–8
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
DL-alpha-Tocopherol acetate all-rac-alpha-Tocopheryl acetate (+-)-alpha-Tocopherol acetate Alpha-tocopherol acetate, dl- Tocopheryl Acetate, dl-Alpha Alpha-tocopheryl acetate, dl- Vitamin E acetate dl- RefChem:1083891 Tocopheryl acetate,dl-alpha d,l-alpha-Tocopherol Acetate Tocopheryl acetate Vitamin E acetate
Compatibility
Works well with:
Retinyl Palmitate Niacinamide Hyaluronic Acid Glycerin Dimethicone Jojoba Oil Caprylic/Capric Triglyceride Cetyl Alcohol Shea Butter Panthenol
Use caution with:
L-Ascorbic Acid Strong Oxidizing Agents
Tocopheryl Acetate is the esterified, stabilized form of Vitamin E and is generally well-tolerated across most formulations. High concentrations of L-Ascorbic Acid can potentially compete or interfere in oxidation-reduction dynamics, though this interaction is less pronounced than with free tocopherol. It must be dispersed in the oil phase during formulation as it is not water-soluble.
Formulation notes
Tocopheryl Acetate requires enzymatic hydrolysis to convert to active tocopherol on skin; efficacy as a direct antioxidant in-formula is lower than free tocopherol, but it offers superior stability. EU Cosmetics Regulation permits use without specific concentration restriction at cosmetic levels; typically used at 0.1–1% for antioxidant protection of both formula and skin. Non-irritating and considered safe for leave-on and rinse-off applications.
Related ingredients
- TocopherolAntioxidant
- BakuchiolActive
- BisabololActive
- LecithinEmulsifier
- RetinolActive
- Ascorbic AcidAntioxidant