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Resveratrol

Resveratrol is a antioxidant, active, anti-aging, soothing used in cosmetic and personal-care formulation. Typical use level is 0.01%–1%. It is both-soluble. Stable in the pH 4–7 range.

At a glance

CAS number
501-36-0
INCI name
Resveratrol
Function
antioxidant, active, anti-aging, soothing
Typical use level
0.01%–1%
Solubility
both
Stable pH
4–7

CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.

Also known as

trans-Resveratrol 3,5,4'-trihydroxystilbene Polygonum cuspidatum extract (resveratrol-rich) Vitis vinifera stilbene

Compatibility

Works well with:
Niacinamide Vitamin C (Ascorbic Acid) Hyaluronic Acid Ferulic Acid Tocopherol Peptides

Use caution with:
High pH alkaline systems Prolonged UV exposure (free form)

Resveratrol is sensitive to oxidation and UV light; encapsulation or inclusion of antioxidant synergists such as ferulic acid and tocopherol significantly improves stability. It is best formulated in slightly acidic to neutral pH environments (4.0–7.0), as alkaline conditions promote degradation. Avoid prolonged exposure to light and air during manufacturing; amber or opaque packaging is strongly recommended.

Formulation notes

Resveratrol is a naturally occurring stilbene polyphenol found in grapes, Japanese knotweed, and berries, prized in cosmetics for its potent antioxidant, anti-inflammatory, and anti-aging properties. It helps neutralize free radicals, supports collagen synthesis, and may inhibit melanogenesis, making it popular in serums and eye creams. The trans isomer is the biologically active form; formulators should verify raw material purity and isomeric ratio, and handle with care to prevent photo-isomerization to the less active cis form.

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