At a glance
- CAS number
- 97-59-6
- INCI name
- Allantoin
- Function
- active, soothing, keratolytic, skin conditioning, wound healing
- Typical use level
- 0.1%–2%
- Solubility
- water
- Stable pH
- 4–8
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
allantoin 5-Ureidohydantoin Glyoxyldiureide Cordianine Glyoxyldiureid Allantol Sebical Alantan AVC/Dienestrolcream Psoralon Septalan Urea, (2,5-dioxo-4-imidazolidinyl)-
Compatibility
Works well with:
Niacinamide Hyaluronic Acid Panthenol Glycerin Aloe Vera Centella Asiatica Extract Ceramides Peptides Zinc PCA Beta-Glucan
Use caution with:
High concentration Salicylic Acid High concentration L-Ascorbic Acid
Allantoin is generally well-tolerated across most formulation systems. At very low pH (below 4.0), solubility decreases and the molecule can degrade over time, so pairing with high-concentration acidic actives should be done cautiously. It is considered broadly compatible with most cosmetic ingredients and is often used as a calming co-ingredient alongside potentially irritating actives.
Formulation notes
CIR and EU Cosmetics Regulation permit up to 2% in rinse-off and leave-on products. Dissolves slowly in cold water; gentle heating (40–60°C) aids dissolution. Synthesized or derived from urea oxidation; vegan synthetic form widely available. No known sensitization concerns at typical use levels.
Related ingredients
- CaffeineActive
- ResveratrolActive
- Salicylic AcidActive
- Mandelic AcidExfoliant
- Sodium HyaluronateHumectant
- UreaHumectant