At a glance
- INCI name
- Sodium Hyaluronate
- Function
- humectant, active, thickener, skin conditioning
- Typical use level
- 0.01%–2%
- Solubility
- water
- Stable pH
- 4–8
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Compatibility
Works well with:
Glycerin Niacinamide Panthenol Allantoin Aloe Vera Peptides Vitamin C (Ascorbyl Glucoside) Ceramides Retinol Zinc PCA
Use caution with:
High-concentration L-Ascorbic Acid Cationic Surfactants High-concentration Ethanol Quaternary Ammonium Compounds
Cationic surfactants and quaternary compounds can complex with the anionic hyaluronate polymer, causing precipitation or loss of function. Very low pH environments (below 4.0), as used with high-concentration L-Ascorbic Acid, can degrade the polymer chain over time. High ethanol concentrations may cause salting-out or precipitation of the polymer.
Formulation notes
Molecular weight significantly affects skin penetration and feel: low MW (< 50 kDa) penetrates deeper but may trigger inflammation at very high levels; high MW (> 1000 kDa) forms a surface film. Use at 0.1–2.0% for standard humectancy; crosslinked forms (used in injectables) are not appropriate for leave-on cosmetics. Generally regarded as very safe with no regulatory use restrictions in cosmetics.
Related ingredients
- Hyaluronic AcidHumectant
- Polyglutamic AcidHumectant
- Sodium PCAHumectant
- UreaHumectant
- CaffeineActive
- Glycolic AcidActive