At a glance
- CAS number
- 15454-75-8
- INCI name
- Zinc PCA
- Function
- active, sebum regulator, humectant, antimicrobial
- Typical use level
- 0.1%–2%
- Solubility
- water
- Stable pH
- 4–7
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
Zinc Pyrrolidone Carboxylate Zinc L-PCA Zinc 2-Pyrrolidone-5-Carboxylate Zinc Pidolate
Compatibility
Works well with:
Niacinamide Salicylic Acid Hyaluronic Acid Glycerin Panthenol Allantoin
Use caution with:
high concentrations of EDTA strongly alkaline ingredients
Zinc PCA performs best in mildly acidic to neutral formulations; strongly alkaline pH can cause precipitation or reduced efficacy. High levels of chelating agents like EDTA may complex the zinc ion and diminish its activity. It is generally well-tolerated alongside other water-soluble actives and humectants.
Formulation notes
Zinc PCA is the zinc salt of pyrrolidone carboxylic acid (PCA), a naturally occurring amino acid derivative found in skin. It is widely used in oily and acne-prone skin formulations for its ability to regulate sebum production, reduce shine, and provide mild antimicrobial activity against Cutibacterium acnes. It also contributes a secondary humectant benefit due to the PCA moiety, making it suitable for balancing moisture while controlling excess oil.
Frequently asked questions
What is Zinc PCA?
Zinc PCA is a active, sebum regulator, humectant, antimicrobial used in cosmetic and personal-care formulation. Typical use level is 0.1%–2%. It is water-soluble. Stable in the pH 4–7 range.
What is Zinc PCA used for?
Zinc PCA is used as active, sebum regulator, humectant, antimicrobial in cosmetic and personal-care formulations.
What is the typical use level of Zinc PCA?
Zinc PCA is typically used at 0.1%–2% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Zinc PCA?
The CAS registry number for Zinc PCA is 15454-75-8. Its INCI name is Zinc PCA.
At what pH is Zinc PCA stable?
Zinc PCA is generally stable in the pH 4–7 range.
What ingredients are compatible with Zinc PCA?
Zinc PCA works well with Niacinamide, Salicylic Acid, Hyaluronic Acid, Glycerin, Panthenol, Allantoin. Use caution when combining it with high concentrations of EDTA, strongly alkaline ingredients.
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