HomeIngredient LibraryEctoine

Active

Ectoine

Ectoine is a humectant, skin-protective, anti-inflammatory, barrier repair used in cosmetic and personal-care formulation. Typical use level is 0.1%–2%. It is water-soluble. Stable in the pH 4–8 range.

At a glance

CAS number
96702-03-3
INCI name
Ectoine
Function
humectant, skin-protective, anti-inflammatory, barrier repair
Typical use level
0.1%–2%
Solubility
water
Stable pH
4–8

CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.

Also known as

1,4,5,6-Tetrahydro-2-methyl-4-pyrimidinecarboxylic acid Tetrahydromethylpyrimidine carboxylic acid THM carboxylic acid Aminoectoine

Compatibility

Works well with:
Hyaluronic Acid Niacinamide Panthenol Ceramides Allantoin Glycerin

Ectoine is broadly compatible with most cosmetic actives and is stable across a wide pH range, making it easy to incorporate into aqueous phases. It works synergistically with other skin-barrier and moisturizing ingredients such as hyaluronic acid and ceramides. No significant incompatibilities with common cosmetic ingredients have been widely documented.

Formulation notes

Ectoine is a naturally occurring extremolyte produced by halophilic microorganisms to protect against osmotic stress, UV radiation, and desiccation. In cosmetics, it stabilizes cellular membranes, proteins, and DNA, reducing inflammation and reinforcing the skin barrier — making it especially valued in sensitive-skin, anti-pollution, and sun-aftercare formulations. It is generally considered very well tolerated with a favorable safety profile.

Related ingredients

Formulate with Ectoine — first formula free

Tell us what you're making. We'll set you up in the AJ Cosmo Labs app with your idea loaded and your first AI formulation free.

Free to start · no credit card · we email you a link to pick up in the app.

Formulating with Ectoine?

Connect with vetted cosmetic chemists and custom labs on AJ Cosmo Labs.

Get on the App Store