HomeIngredient LibraryHydroxypropyl Methylcellulose

Thickener

Hydroxypropyl Methylcellulose

Hydroxypropyl Methylcellulose is a thickener, film_former, emulsifier, humectant used in cosmetic and personal-care formulation. Typical use level is 0.1%–5%. It is water-soluble. Stable in the pH 3–11 range.

At a glance

CAS number
9004-65-3
INCI name
Hydroxypropyl Methylcellulose
Function
thickener, film_former, emulsifier, humectant
Typical use level
0.1%–5%
Solubility
water
Stable pH
3–11

CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.

Also known as

HPMC Hypromellose Methocel Methylhydroxypropylcellulose Cellulose Hydroxypropyl Methyl Ether

Compatibility

Works well with:
Glycerin Propylene Glycol Carbomer Sodium Hyaluronate Panthenol Niacinamide

Use caution with:
High concentrations of electrolytes Strongly oxidizing agents

HPMC disperses readily in cold water and hydrates upon heating or prolonged mixing; it should not be added to hot water directly as it can form lumps. High salt concentrations can reduce viscosity and may cause salting-out at elevated electrolyte levels. It is generally compatible with a broad range of cosmetic actives and preservatives within its stable pH range.

Formulation notes

Hydroxypropyl Methylcellulose is a semisynthetic cellulose ether widely used in cosmetics as a thickener, film former, and rheology modifier for gels, lotions, and eye drops. It provides a smooth, non-tacky skin feel and forms a flexible film on skin and hair that can improve moisture retention. It is considered low-irritancy, non-ionic, and suitable for sensitive skin formulations.

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