At a glance
- CAS number
- 78418-01-6
- INCI name
- Capryloyl Salicylic Acid
- Function
- exfoliant, keratolytic, sebostatic, active
- Typical use level
- 0.1%–2%
- Solubility
- oil
- Stable pH
- 4–6.5
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
LHA Lipohydroxy Acid Beta-Lipohydroxy Acid Capryloyl Beta-Hydroxy Acid C8 Salicylic Acid
Compatibility
Works well with:
Niacinamide Glycerin Ceramides Hyaluronic Acid Retinol Zinc PCA
Use caution with:
High pH buffers Strongly alkaline actives
Capryloyl Salicylic Acid is most stable and effective in acidic to mildly acidic formulations (pH 4–6.5); alkaline conditions can hydrolyze the capryloyl ester bond, degrading it back toward salicylic acid. Its lipophilic nature makes it ideally suited for oil-in-water emulsions and anhydrous systems rather than purely aqueous formulas. It pairs well with other resurfacing and barrier-supporting actives without known antagonistic interactions at recommended use levels.
Formulation notes
Capryloyl Salicylic Acid is a lipophilic derivative of salicylic acid developed by L'Oréal, in which an eight-carbon fatty chain is esterified to salicylic acid, giving it superior skin affinity and a milder, more targeted exfoliating profile. It works by selectively loosening the cohesion of corneocytes at the skin surface and within follicular infundibula, making it particularly effective for refining texture, addressing comedones, and improving oily or acne-prone skin. Because its larger molecular size limits deeper penetration compared to free salicylic acid, it is generally considered less irritating and well-tolerated even in sensitive-skin formulations.
Frequently asked questions
What is Capryloyl Salicylic Acid?
Capryloyl Salicylic Acid is a exfoliant, keratolytic, sebostatic, active used in cosmetic and personal-care formulation. Typical use level is 0.1%–2%. It is oil-soluble. Stable in the pH 4–6.5 range.
What is Capryloyl Salicylic Acid used for?
Capryloyl Salicylic Acid is used as exfoliant, keratolytic, sebostatic, active in cosmetic and personal-care formulations.
What is the typical use level of Capryloyl Salicylic Acid?
Capryloyl Salicylic Acid is typically used at 0.1%–2% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Capryloyl Salicylic Acid?
The CAS registry number for Capryloyl Salicylic Acid is 78418-01-6. Its INCI name is Capryloyl Salicylic Acid.
At what pH is Capryloyl Salicylic Acid stable?
Capryloyl Salicylic Acid is generally stable in the pH 4–6.5 range.
What ingredients are compatible with Capryloyl Salicylic Acid?
Capryloyl Salicylic Acid works well with Niacinamide, Glycerin, Ceramides, Hyaluronic Acid, Retinol, Zinc PCA. Use caution when combining it with High pH buffers, Strongly alkaline actives.
Related ingredients
- Mandelic AcidExfoliant
- Salicylic AcidActive
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