At a glance
- CAS number
- 90-80-2
- INCI name
- Gluconolactone
- Function
- exfoliant, humectant, antioxidant, chelator
- Typical use level
- 3%–12%
- Solubility
- water
- Stable pH
- 3.5–7
CAS number and synonyms are sourced from PubChem. Function, usage levels, pH and compatibility are AI-assisted formulation guidance — verify against your supplier's technical data sheet and applicable regulations before use.
Also known as
D-Glucono-delta-lactone D-Gluconolactone GDL Glucono delta-lactone 1,5-Gluconolactone
Compatibility
Works well with:
Niacinamide Hyaluronic Acid Lactobionic Acid Glycerin Aloe Vera Panthenol
Use caution with:
High-pH alkaline actives
Gluconolactone hydrolyzes to gluconic acid in aqueous solution, lowering formula pH, so it functions best and remains stable in formulas kept below pH 7. It is generally well-tolerated alongside other polyhydroxy acids and humectants. Avoid combining with strongly alkaline ingredients such as high-concentration sodium bicarbonate or high-pH amino acids, as these will neutralize its acidic activity and may cause instability.
Formulation notes
Gluconolactone is a polyhydroxy acid (PHA) that provides gentle chemical exfoliation by promoting desquamation of dead skin cells while simultaneously acting as a humectant through its multiple hydroxyl groups. Because its molecule is larger than AHAs like glycolic acid, it penetrates more slowly, making it significantly less irritating and suitable for sensitive or reactive skin types. It also chelates metal ions, offering mild antioxidant protection and potential preservation-boosting effects in formulations.
Frequently asked questions
What is Gluconolactone?
Gluconolactone is a exfoliant, humectant, antioxidant, chelator used in cosmetic and personal-care formulation. Typical use level is 3%–12%. It is water-soluble. Stable in the pH 3.5–7 range.
What is Gluconolactone used for?
Gluconolactone is used as exfoliant, humectant, antioxidant, chelator in cosmetic and personal-care formulations.
What is the typical use level of Gluconolactone?
Gluconolactone is typically used at 3%–12% in the finished formulation. Always confirm against your supplier's technical data sheet.
What is the CAS number of Gluconolactone?
The CAS registry number for Gluconolactone is 90-80-2. Its INCI name is Gluconolactone.
At what pH is Gluconolactone stable?
Gluconolactone is generally stable in the pH 3.5–7 range.
What ingredients are compatible with Gluconolactone?
Gluconolactone works well with Niacinamide, Hyaluronic Acid, Lactobionic Acid, Glycerin, Aloe Vera, Panthenol. Use caution when combining it with High-pH alkaline actives.
Related ingredients
- Citric AcidPh Adjuster
- Phytic AcidChelator
- Glycolic AcidActive
- Lactic AcidPh Adjuster
- Sodium GluconateChelator
- Sodium PhytateChelator