The most evidence-backed HEV-protective actives are lutein, zeaxanthin, astaxanthin, and low-concentration iron oxides (0.1–0.5%), which physically scatter high-energy visible light. Niacinamide and tocopherol acetate are common supporting antioxidants. A cosmetic chemist on AJ Cosmo Labs can recommend an active stack matched to your claims strategy and target price point.
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