Yes — this is one of the most compatible active pairings in cosmetic formulation. Niacinamide at 5% is frequently used alongside encapsulated retinol at 0.1–1% in moisturisers and night serums. Both are stable at pH 5–6, and niacinamide helps mitigate the irritation retinoids can cause. Cosmetic chemists on AJ Cosmo Labs regularly develop retinol-plus-niacinamide briefs for indie brands.
Read the full guide on Niacinamide compatibility →