Yes — tranexamic acid is compatible with niacinamide and is commonly co-formulated with it for synergistic brightening effects. Vitamin C (ascorbic acid) combinations require more care due to pH conflict and oxidation sensitivity, though stabilized vitamin C derivatives like ascorbyl glucoside are more compatible. An experienced cosmetic chemist will run compatibility and stability testing on any multi-active combination. Browse specialist formulators on AJ Cosmo Labs to find the right expertise for your formula.
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